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LyoPharm


GMP production freeze dryers

From 2 to 45 m² of shelf area / Condenser capacity up to 800 kg / Output for 2R up to 200,000 vials

Model LyoPharm
Shelf area 800 x 900 mm 1,200 x 1,200 mm 1,500 x 1,600 mm 1,500 x 2,000 mm
Shelf area (m²) 2.16 2.88 3.6 4.32 5.04 5.76 7.2 8.64 10.08 11.52 12.96 14.4 16.8 19.2 21.6 24 26.4 28.8 30 33 36 39 42 45
Nº of shelves 3 4 5 6 7 8 5 6 7 8 9 10 7 8 9 10 11 12 10 11 12 13 14 15
Shelves clearance (mm) 105 90 75 105 90 75 105 90 75 105 90 75 105 90 75 105 90 75 105 90 75 105 90 75
Chamber width 2,000 mm 2,300 mm 2,500 mm 2,500 mm
Chamber height 2,200 mm 2,500 mm 2,500 mm 2,900 mm 2,500 2,900 mm 3,400 mm 3,400 mm 3,600 mm
Condenser capacity (kg) 40 45 50 65 80 80 120 150 200 200 250 250 300 350 400 450 450 500 600 800
Trays 300 x 400 mm 300 x 400 mm 300 x 400 mm 300 x 400 mm
Condenser temperature -85 ºC -85 ºC -85 ºC -85 ºC
Shelves temperature range from -60ºC to +85ºC from -60ºC to +85ºC from -60ºC to +85ºC from -60ºC to +85ºC

Optional equipment

  • The chamber
    • Rectangular chamber
    • Pressureless vessel
    • Injected foam insulation
    • Cooling by cold water circuit
  • Connection with condenser
    • Butterfly valve
    • Mushroom valve
    • Bottom shelf closing
  • Ice condenser
    • Integrated underneath, on the same floor
    • Integrated on the side, on the same floor
    • Outside, behind the camera, on the same floor
    • Outside, under the camera, on another floor
  • Shelves movement
    • Closing system hydraulic piston 
    • Bellows
    • Connection with the automatic charging system
  • CIP
    • Chamber and condenser cleaning system
    • Recirculation system with heating
    • Multiple cleaning cycles
  • SIP
    • PED-EN13445
    • ASME
    • Chamber cool-down after SIP
  • Plant distribution
    • 1st floor
    • 2 floors
    • Passthrough system
  •  Additional elements
    • ATEX (processed with solvents and alcohol)
    • Cold tray loading
    • Frozen tray loading
    • Nucleation technology
  • Refrigeration
    • Piston compressor
    • Screw compressor
    • Liquid nitrogen system
    • Cascade system
    • Cooling system without PCA
    • Compressed air system
  • Door
    • Full size door
    • Automatic locking
    • Slot front door (constant loading level)
    • Full size sub-door
    • Cooling by cold water circuit
  • Process sensors
    • Pirani
    • Capacitive
    • Temperature probes (Pt-100 / Thermocouple)
    • Redundant temperature probes (Pt-100 / Thermocouple)
    • Wireless temperature monitoring
    • Full batch traceability software
  • Control systems
    • Rockwell / Siemens Automation PLC
    • Integrated HMI
    • SCADA
    • Electronic recorder
    • Electronic Server and Think Client
    • Cycle optimization technology
  • Filter vent system
    • Sterilizable
    • Ports for integrity testing
    • Secondary venting cycle
    • Secondary vent filter
    • Water filter integrity test
  • Vacuum system
    • Sealed vacuum pumps with blowing system
    • Redundancy (additional pump)
    • Dry pumps with blowing system

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