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LyoNano


GMP production freeze dryers for small batches

From 0.5 to 2.5 m² of shelf area / Condenser apacity up to 40 kg / Output for 2R up to 10,000 vials

  • Compact construction complying with GMP
  • CIP / SIP equipment
  • Wide range of optional equipment
  • Panels for clean rooms
Model LyoNano
Shelf area 0.5 m² 1 m² 1.5 m² 2 m²
Shelf dimensions 380 x 450 mm
Nº of shelves 3 + 1 6 + 1 9 + 1 12 + 1
Shelves clearance 90 mm 75 mm 90 mm 65 mm
Chamber material Stainless steel AISI 316L
Condenser capacity 30 kg 30 kg 40 kg 40 kg
Condenser temperature -85 ºC
Shelves temperature range from -60 ºC to +85 ºC
Dimensions (W x D x H) 1,600 x 1,300 x 1,800 mm 2,500 x 1,300 x 1,800 mm
Weight 1,500 kg 2,000 kg 2,500 kg 3,000 kg

Optional equipment

  • The chamber
    • Rectangular chamber
    • Pressureless vessel
    • Injected foam insulation
    • Cooling by cold water circuit
  • Connection with condenser
    • Butterfly valve
    • Mushroom valve
    • Bottom shelf closing
  • Ice condenser
    • Integrated underneath, on the same floor
    • Integrated on the side, on the same floor
    • Outside, behind the camera, on the same floor
    • Outside, under the camera, on another floor
  • Shelves movement
    • Closing system hydraulic piston 
    • Bellows
    • Connection with the automatic charging system
  • CIP
    • Chamber and condenser cleaning system
    • Recirculation system with heating
    • Multiple cleaning cycles
  • SIP
    • PED-EN13445
    • ASME
    • Chamber cool-down after SIP
  • Plant distribution
    • 1st floor
    • 2 floors
    • Passthrough system
  •  Additional elements
    • ATEX (processed with solvents and alcohol)
    • Cold tray loading
    • Frozen tray loading
    • Nucleation technology
  • Refrigeration
    • Piston compressor
    • Screw compressor
    • Liquid nitrogen system
    • Cascade system
    • Cooling system without PCA
    • Compressed air system
  • Door
    • Full size door
    • Automatic locking
    • Slot front door (constant loading level)
    • Full size sub-door
    • Cooling by cold water circuit
  • Process sensors
    • Pirani
    • Capacitive
    • Temperature probes (Pt-100 / Thermocouple)
    • Redundant temperature probes (Pt-100 / Thermocouple)
    • Wireless temperature monitoring
    • Full batch traceability software
  • Control systems
    • Rockwell / Siemens Automation PLC
    • Integrated HMI
    • SCADA
    • Electronic recorder
    • Electronic Server and Think Client
    • Cycle optimization technology
  • Filter vent system
    • Sterilizable
    • Ports for integrity testing
    • Secondary venting cycle
    • Secondary vent filter
    • Water filter integrity test
  • Vacuum system
    • Sealed vacuum pumps with blowing system
    • Redundancy (additional pump)
    • Dry pumps with blowing system

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