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filling and closing machines

Enfarma Vol. 16 No. 5. Filling and closing machines for automatic processing of eye drops and nasal sprays.

Press release
01 de November de 2015


Filling and closing machines for automatic processing of eye drops and nasal sprays.

The equipment we present is a compact filling and closing machine for automatic processing of vials and bottles in glass, plastic, or metal, for liquid, semisolid, and powder products, in sterile areas or clean rooms.

Production speed: up to 9,000 units per hour. Dosing volumes from 0.1 up to 1,050 ml.

The design has been made for use in sterile areas, in compliance with cGMP and US FDA regulations, and in special accordance with the requirements of the pharmaceutical, biotech, cosmetic, chemical and similar industries.

The filling station is equipped with a peristaltic pump, valveless rotary piston pump, or powder doser.

Using “CIP-SIP” construction elements, it is not necessary to remove the product contact parts for cleaning or sterilizing.

The pick & place station places droppers and caps onto bottles sequentially, using vacuum.

The closing station of this tilling and closing machine is equipped with a servo head for difficult screw closures.

All closures currently used can be easily handled, such as:

  • Snap-on / screw caps.
  • Childproof caps.
  • Spray / dosing pumps.
  • Droppers.

Feeding of different kinds of droppers and caps is done automatically by vibrating feeders, made of AISI-316L stainless steel.

In order to work in sterile or clean room conditions, Dara provide different solutions, such as LAF, RABS, or isolators.

Using an isolator or RABS system improves the sterile conditions and offers a better protection of the product and for the user.

Optional equipment:

  • Dosing control through micro scale and automatic recalibration of the volume to be dosed.
  • Gas flushing before, during, or after the filling process.
  • Bulk vibratory hoppers for droppers and caps.
  • Automatic rejection of defective containers.
  • Data recording software to export the production data in compliance with 21CFR part 11. 
  • Laminar flow unit / RABS / Isolator unit.
  • IQ / OQ Validation package.
  • Printing / Codification.
filling and closing machines