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LyoPro

GMP production freeze dryers for large scale production

From 16 to 45 m² of shelf area / Condenser capacity up to 800 kg / Output for 2R up to 200,000 vials

Model	LyoPro
Shelf dimensions	1,500 x 1,600 mm						1,500 x 2,000 mm
Shelf area	16.8 m²	19.2 m²	21.6 m²	24 m²	26,4 m²	28,8 m²	30 m²	33 m²	36 m²	39 m²	42 m²	45 m²
Nº of shelves	7	8	9	10	11	12	10	11	12	13	14	15
Shelves clearance (mm)	105	90	75	105	90	75	105	90	75	105	90	75
Chamber width	2,300 mm						2,300 mm
Chamber height	4.200 mm						4.400 mm			4.600 mm
Condenser capacity (kg)	300 kg	350 kg	400 kg	450 kg	450 kg	500 kg	600 kg			800 kg
Condenser temperature	-85 ºC
Shelves temperature range	from -60 ºC to +85 ºC

Optional equipment

The chamber
- Rectangular chamber
- Pressureless vessel
- Injected foam insulation
- Cooling by cold water circuit

Connection with condenser
- Butterfly valve
- Mushroom valve
- Bottom shelf closing

Ice condenser
- Integrated underneath, on the same floor
- Integrated on the side, on the same floor
- Outside, behind the camera, on the same floor
- Outside, under the camera, on another floor

Shelves movement
- Closing system hydraulic piston
- Bellows
- Connection with the automatic charging system

CIP
- Chamber and condenser cleaning system
- Recirculation system with heating
- Multiple cleaning cycles

SIP
- PED-EN13445
- ASME
- Chamber cool-down after SIP

Plant distribution
- 1st floor
- 2 floors
- Passthrough system

Additional elements
- ATEX (processed with solvents and alcohol)
- Cold tray loading
- Frozen tray loading
- Nucleation technology

Refrigeration
- Piston compressor
- Screw compressor
- Liquid nitrogen system
- Cascade system
- Cooling system without PCA
- Compressed air system

Door
- Full size door
- Automatic locking
- Slot front door (constant loading level)
- Full size sub-door
- Cooling by cold water circuit

Process sensors
- Pirani
- Capacitive
- Temperature probes (Pt-100 / Thermocouple)
- Redundant temperature probes (Pt-100 / Thermocouple)
- Wireless temperature monitoring
- Full batch traceability software

Control systems
- Rockwell / Siemens Automation PLC
- Integrated HMI
- SCADA
- Electronic recorder
- Electronic Server and Think Client
- Cycle optimization technology

Filter vent system
- Sterilizable
- Ports for integrity testing
- Secondary venting cycle
- Secondary vent filter
- Water filter integrity test

Vacuum system
- Sealed vacuum pumps with blowing system
- Redundancy (additional pump)
- Dry pumps with blowing system

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