Multiformat-line-for-aseptic-packaging
The continuous evolution and development of new inactivated, attenuated, or viral vector-based vaccines, as well as their dispensing methods, make adaptation to a versatile aseptic packaging system essential. Dara Pharma has evolved in this direction, integrating complete lines, Turn-Key Solutions, which make the vaccine packaging process more profitable.
Great versatility with different types of packaging —vials, cartridges, and syringes—, and quick format changeover.
For formats supplied in bulk and RTU (Ready-to-use).
Dosing of liquid and powder products, as well as integration with a freeze drying process.
The sequence of vial processing in bulk starts with the loading of vials into the washer.
More informationDara Pharma's linear and rotary washing machines have been designed for maximum efficiency, low consumption, and high flexibility to process the maximum number of formats.
More informationDara Pharma's modular sterilization and depyrogenation equipment has been designed to process glass containers efficiently and continuously. In addition to being easily adaptable to customer requirements, these solutions provide lower energy consumption in production.
More informationThe processing sequence of RTU vials, syringes and cartridges starts with the debagging module, which automatically and efficiently removes the bag from the nest or tray.
More informationThe processing of RTU formats continues with the delidding, in which the Tyvek lid and the inner liner that protects the contents of the nest or tray are removed.
More informationThe compact denesting equipment allows fast and accurate unloading of vials, syringes, and cartridges for subsequent individual processing.
More informationDara Pharma's aseptic filling solutions stand out for their versatility and precision in the dosing of vials, syringes and cartridges for liquid and powder products. The closing machines control and measure multiple parameters during this process to guarantee the complete tightness of the product, such as crimping pressure, closing height, or any visual control.
More informationAutomatic vial loading and unloading systems have been designed to connect the filling line with the freeze dryer. The implementation of this equipment aims not only to increase the efficiency of the line, but also to reduce potential cross-contamination in this process.
More informationLyophilization is a drying process that removes solvent by sublimation and not boiling like other drying processes. Sublimation is a product changing from a solid to a gas without passing through an intermediate liquid phase. As a result, the product with much more powerful active ingredients and nearly immediate reconstitution time is obtained.
More informationOnce vials have been freeze dried, the high-speed linear closing machine guarantees that any product complies 100% with the established requirements using different types of aluminum closures.
More informationThe external washing machine is incorporated at the end of the filling line to achieve an external cleaning of the containers to remove any impurities.
More informationThe line has a washing machine and a sterilization and depyrogenation tunnel for bulk supply.
Cleaning
Maximum efficiency and high flexibility to process as many formats as possible: vials, bottles, or cartridges.
Sterilization & Depyrogenation
Maximum flexibility and adaptability, low consumption, and easy maintenance thanks to its modular design.
for vials
for vials and cartridges
Debagging, delidding and denesting are available for supply in nest and tray.
Debbaging
Deliding
Denesting
Dara Pharma's filling solutions have revolutionized the aseptic packaging machinery sector thanks to their versatility and flexibility. With our solutions, it is possible to process liquid, semi-solid and powder products in the same equipment.
Peristaltic
dosing |
Volumetric
dosing |
Time-pressure
dosing |
|
Liquid |
Pressure-vacuum dosing |
Powder |
Closing is the operation that guarantees the seal of the container. Dara Pharma's closing machines control and measure the parameters required in this process, such as torque, crimp pressure, closing height, and any visual control – guaranteeing that the products are closed in a satisfactory way.
Lyophilization is a drying process that removes solvent by sublimation and not boiling like other drying processes. Sublimation is a product changing from a solid to a gas without passing through an intermediate liquid phase. As a result, the product with much more powerful active ingredients and nearly immediate reconstitution time is obtained.
Extends the shelf life of the product.
The rehydration process is instantaneous.
Maintains the qualitative properties of the product.
Freeze drying
for vials
Closing
External washing
1
Design, manufacture, and adjustment of the transfer systems for the correct integration of all the machines of the line.
2
A control system is configured for the entire line, so that all the machines operate under the same software and data acquisition system.
3
The complete maintenance plan for the entire line ensures that all machines will operate optimally and efficiently in the long term.
We have a team of specialists waiting to answer all your questions and inquiries. Feel free to contact us through this form and we will get in touch with you.